Cardiovascular Simulation, AI, and Structural Heart Intervention Planning
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Simulation-based Surgical Planning

Simulation-based Surgical Planning

Transcatheter Aortic Valve Replacement (TAVR) planning

 Computer models unleash unprecedented predictive abilities and can guide cardiac surgery in the future to minimize uncertainty in patient outcomes, but must facilitate accurate yet quick simulations!

I combined a biomechanics simulation of a balloon-expandable TAVR deployment in a pre-operative personalized aorta model with ViCar3D CFD solver and a versatile + efficient prosthetic valve dynamics model from my PhD research to predict post-operative valve shape and associated hemodynamics.

Such simulations can rapidly provide a priori knowledge of valvular performance in different deployment configurations. This information enables clinicians to determine best deployment parameters and minimize future risks of structural as well as hemodynamic complications.

Credits:
TAV Deployment Simulation: Fateme Esmailie, Huang Chen & Lakshmi Dasi
Co-authors: Jung Hee Seo & Rajat Mittal